[中文名稱] 密花綿毛葉菊素異丁烯酸酯
[英文名稱] Erioflorin methacrylate
[別 名] 柄花菊異丁烯酯
[化學名稱] 2-Propenoic acid, 2-methyl-, 1a, 2, 3, 5a, 7, 8, 8a, 9, 10, 10a-decahydro-4, 10a-dimethyl-8-methylene-7-oxooxireno [5,6] cyclodeca [1,2-b] furan-3, 9-diyl ester [1aR-(1aR,3S*, 4Z, 5a$*, 8aR*, 9R*, 10aR*)]-
[分 子 式] C23H28O7;
[分 子 量] 416.45
[物理性質(zhì)] 熔點155～158°(己烷-醋酸乙酯), [α]D-87°(c=1.0, 氯仿). NMR(CDCl3)τ: 8.10 (d, J=1.5, C4-Me), 8.60 (s, C10-CH3), 4.28, 3.80 (d, J=2.0, C11-CH2), 7.30 (dd, J=4, 10, H-1), 8.22 (ddd, J=2, 10, 14.5, H-2), 7.50 (ddd,J=4,5,14.5,H-2), 4.80 (dd,J=2,5,H-3), 4.80 (dq,J=11, 1.5,H-5), 3.80 (dd,J=2,11,H-6), 7.10 (m,H-7), 4.85 (m,J=4.5,2,H-8), 7.2 (dd,J=4.5,15.5,H-9), 8.60 (dd,J=2,15,H-9); IRνCHCl3maxcm-1: 1760, 1715, 1666, 1630, 1160, 1130; UVλ EtOHmax nm (ε): 211 (24700); MS m/e: 416 (M+), 347 (M+-異 丁烯酸), 330 (M+- 異丁烯酸), 261, 240, (M+-二個異丁烯酸), 83, 69, 55.
[成分分類] 萜類
[藥理作用] 對小鼠淋巴細胞白血病P388 (PS)有抑制作用。
[毒 性]
[不良反應(yīng)]
[用 途] 抗腫瘤
[成分來源] 菊科植物柄花菊 Podanthus ovatifolius Lag. 莖, ^c葉[1], ^b米梯柄花菊 P. mitiqui ^c莖, ^c葉[2]。
[英文名稱] Erioflorin methacrylate
[別 名] 柄花菊異丁烯酯
[化學名稱] 2-Propenoic acid, 2-methyl-, 1a, 2, 3, 5a, 7, 8, 8a, 9, 10, 10a-decahydro-4, 10a-dimethyl-8-methylene-7-oxooxireno [5,6] cyclodeca [1,2-b] furan-3, 9-diyl ester [1aR-(1aR,3S*, 4Z, 5a$*, 8aR*, 9R*, 10aR*)]-
[分 子 式] C23H28O7;
[分 子 量] 416.45
[物理性質(zhì)] 熔點155～158°(己烷-醋酸乙酯), [α]D-87°(c=1.0, 氯仿). NMR(CDCl3)τ: 8.10 (d, J=1.5, C4-Me), 8.60 (s, C10-CH3), 4.28, 3.80 (d, J=2.0, C11-CH2), 7.30 (dd, J=4, 10, H-1), 8.22 (ddd, J=2, 10, 14.5, H-2), 7.50 (ddd,J=4,5,14.5,H-2), 4.80 (dd,J=2,5,H-3), 4.80 (dq,J=11, 1.5,H-5), 3.80 (dd,J=2,11,H-6), 7.10 (m,H-7), 4.85 (m,J=4.5,2,H-8), 7.2 (dd,J=4.5,15.5,H-9), 8.60 (dd,J=2,15,H-9); IRνCHCl3maxcm-1: 1760, 1715, 1666, 1630, 1160, 1130; UVλ EtOHmax nm (ε): 211 (24700); MS m/e: 416 (M+), 347 (M+-異 丁烯酸), 330 (M+- 異丁烯酸), 261, 240, (M+-二個異丁烯酸), 83, 69, 55.
[成分分類] 萜類
[藥理作用] 對小鼠淋巴細胞白血病P388 (PS)有抑制作用。
[毒 性]
[不良反應(yīng)]
[用 途] 抗腫瘤
[成分來源] 菊科植物柄花菊 Podanthus ovatifolius Lag. 莖, ^c葉[1], ^b米梯柄花菊 P. mitiqui ^c莖, ^c葉[2]。