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20世紀(jì)50年代
In the 1950s,
抑郁癥絕對是一件隱秘的事情
depression was a strictly private affair.
那些尋求幫助的人幾乎得不到回饋
Those that sought help got little in return.
只存在的寥寥數(shù)種藥物
The few drugs that were
卻幾乎無法改善人們的心情
on offer were unlikely to lift your spirits.
你會遇到口干
You would have dry mouth,
視線模糊 排尿困難的問題
blurred vision, problems passing urine.
你會覺得神志不清 反應(yīng)遲鈍
You'd feel knocked out and dopey.
這種狀況比你
It would be barely better
服藥前的情況好不了多少
than the situation you were actually in to start with.
一種新藥物的到來 改變了這一切
It all changed when a new wave of drugs came along.
科學(xué)家意識到 一種大腦中的化學(xué)物質(zhì)
Scientists had realised that a brain chemical,
血清素 影響著我們的情緒
serotonin, affects our mood.
如果他們能夠找到一種
If they could find a way to boost
提高大腦中血清素含量的方法
the amount of serotonin in the brain,
就能夠提高我們的幸福感
it could improve our sense of wellbeing.
他們檢驗了數(shù)百種化合物
They tested hundreds of compounds
最終成功研制出了一種藥物
and managed to create a new class of drugs
它消除了
that had a fraction of the
傳統(tǒng)抑郁癥治療藥物的副作用
side effects of the older anti-depressants.
這組化合物被命名為
This group was termed
選擇性血清素再吸收抑制劑
selective serotonin re-uptake inhibitors,
簡稱SSRIs
SSRIs.
很快人們便熟知了其商品名
Soon they were known simply by the
這也是市場上首次出現(xiàn)此類藥物 百憂解
brand name of the first one on the market, Prozac.
20世紀(jì)50年代
In the 1950s,
抑郁癥絕對是一件隱秘的事情
depression was a strictly private affair.
那些尋求幫助的人幾乎得不到回饋
Those that sought help got little in return.
只存在的寥寥數(shù)種藥物
The few drugs that were
卻幾乎無法改善人們的心情
on offer were unlikely to lift your spirits.
你會遇到口干
You would have dry mouth,
視線模糊 排尿困難的問題
blurred vision, problems passing urine.
你會覺得神志不清 反應(yīng)遲鈍
You'd feel knocked out and dopey.
這種狀況比你
It would be barely better
服藥前的情況好不了多少
than the situation you were actually in to start with.
一種新藥物的到來 改變了這一切
It all changed when a new wave of drugs came along.
科學(xué)家意識到 一種大腦中的化學(xué)物質(zhì)
Scientists had realised that a brain chemical,
血清素 影響著我們的情緒
serotonin, affects our mood.
如果他們能夠找到一種
If they could find a way to boost
提高大腦中血清素含量的方法
the amount of serotonin in the brain,
就能夠提高我們的幸福感
it could improve our sense of wellbeing.
他們檢驗了數(shù)百種化合物
They tested hundreds of compounds
最終成功研制出了一種藥物
and managed to create a new class of drugs
它消除了
that had a fraction of the
傳統(tǒng)抑郁癥治療藥物的副作用
side effects of the older anti-depressants.
這組化合物被命名為
This group was termed
選擇性血清素再吸收抑制劑
selective serotonin re-uptake inhibitors,
簡稱SSRIs
SSRIs.
很快人們便熟知了其商品名
Soon they were known simply by the
這也是市場上首次出現(xiàn)此類藥物 百憂解
brand name of the first one on the market, Prozac.