英語(yǔ)資源頻道為大家整理的雙語(yǔ)新聞閱讀:美國(guó)科學(xué)家發(fā)現(xiàn)永葆青春的基因,供大家閱讀參考。
'Fountain of youth' gene is discovered - and scientists say it could help heal wounds
A ‘fountain of youth gene’ has been identified by scientists.Experts have long been puzzled as to why young animals recover from injuries more quickly than adults. The gene, Lin28a, is highly active in unborn children, but does less and less with age.
In tests on mice, it quickened the healing of wounds and sped up regrowth after a patch of fur was shaved.
It also helped repair tissues in the ear after they were injured.Lin28a achieved all of these effects by increasing the production of several metabolicenzymes and enhancing metabolic processes that are normally more active in embryos.
The Harvard Medical School scientists hope that waking the gene up in the adult body could speed up the healing of wounds after operations.
Researcher George Daley said it may be possible to produce a drug that has the same effect as the gene.
He added: ‘It sounds like science fiction but Lin28a could be part of a healing cocktail that gives adults the superior tissue repair seen in juvenile animals.’
He said: ‘Why some animals can fully regenerate organs when others cannot is a longstanding mystery of biology.
‘Our studies support the concept that mammalian tissue repair can be substantially improved by engineering the reactivation of genes that regulate juvenile developmental stages.’
The research is published in the journal Cell.
據(jù)英國(guó)《每日郵報(bào)》報(bào)道,美國(guó)哈佛大學(xué)科研人員近日宣布,他們發(fā)現(xiàn)了能使人保持年輕的基因。這組名為L(zhǎng)in28a的基因在未出生的胎兒身上非?;钴S,但隨著人類(lèi)年齡的增長(zhǎng),其功能開(kāi)始逐漸退化。此前,科學(xué)家一直無(wú)法解釋為什么年輕的動(dòng)物在受傷后會(huì)比成年的動(dòng)物恢復(fù)得快。在一組實(shí)驗(yàn)中,科學(xué)家把小白鼠的皮毛剃光,然后發(fā)現(xiàn)Lin28a能夠加快皮毛重生的速度。在另一組實(shí)驗(yàn)中,科學(xué)家發(fā)現(xiàn)Lin28a能夠幫助小白鼠受傷的皮膚組織加速?gòu)?fù)原。研究發(fā)現(xiàn),Lin28a基因能產(chǎn)生多種代謝酶,加快新陳代謝的速度,實(shí)現(xiàn)自我修復(fù)的效果。 科研人員希望能將此項(xiàng)研究成果用于幫助成年病人手術(shù)后的傷口愈合。
'Fountain of youth' gene is discovered - and scientists say it could help heal wounds
A ‘fountain of youth gene’ has been identified by scientists.Experts have long been puzzled as to why young animals recover from injuries more quickly than adults. The gene, Lin28a, is highly active in unborn children, but does less and less with age.
In tests on mice, it quickened the healing of wounds and sped up regrowth after a patch of fur was shaved.
It also helped repair tissues in the ear after they were injured.Lin28a achieved all of these effects by increasing the production of several metabolicenzymes and enhancing metabolic processes that are normally more active in embryos.
The Harvard Medical School scientists hope that waking the gene up in the adult body could speed up the healing of wounds after operations.
Researcher George Daley said it may be possible to produce a drug that has the same effect as the gene.
He added: ‘It sounds like science fiction but Lin28a could be part of a healing cocktail that gives adults the superior tissue repair seen in juvenile animals.’
He said: ‘Why some animals can fully regenerate organs when others cannot is a longstanding mystery of biology.
‘Our studies support the concept that mammalian tissue repair can be substantially improved by engineering the reactivation of genes that regulate juvenile developmental stages.’
The research is published in the journal Cell.
據(jù)英國(guó)《每日郵報(bào)》報(bào)道,美國(guó)哈佛大學(xué)科研人員近日宣布,他們發(fā)現(xiàn)了能使人保持年輕的基因。這組名為L(zhǎng)in28a的基因在未出生的胎兒身上非?;钴S,但隨著人類(lèi)年齡的增長(zhǎng),其功能開(kāi)始逐漸退化。此前,科學(xué)家一直無(wú)法解釋為什么年輕的動(dòng)物在受傷后會(huì)比成年的動(dòng)物恢復(fù)得快。在一組實(shí)驗(yàn)中,科學(xué)家把小白鼠的皮毛剃光,然后發(fā)現(xiàn)Lin28a能夠加快皮毛重生的速度。在另一組實(shí)驗(yàn)中,科學(xué)家發(fā)現(xiàn)Lin28a能夠幫助小白鼠受傷的皮膚組織加速?gòu)?fù)原。研究發(fā)現(xiàn),Lin28a基因能產(chǎn)生多種代謝酶,加快新陳代謝的速度,實(shí)現(xiàn)自我修復(fù)的效果。 科研人員希望能將此項(xiàng)研究成果用于幫助成年病人手術(shù)后的傷口愈合。