A Howard Hughes Medical Institute (HHMI) professor and 138 of his undergraduates have co-authored a paper that provides the first genome-wide estimate of vital genes that are also essential for eye development of the common fruit fly.
Banerjee and his students identified 501 essential genes responsible for processes such as repair, cell death, and cell replication in the fruit fly's developing eye.
They report the results of their research and the impact of their research-based learning project in the February 2005 issue of PLoS (Public Library of Science) Biology.
It won't be easy to find a paper with 138 undergraduate authors, said Banerjee, one of 20 HHMI professors who received $1 million grants in 2002 to improve undergraduate biology education. In fact, this could easily be the first paper ever published with that many undergraduate authors that has serious science in it.
［簡(jiǎn)譯］美國(guó)霍華德-休斯醫(yī)學(xué)研究所的一名教授和他的138名學(xué)生日前發(fā)表了一份研究報(bào)告。這份報(bào)告首次確定了在果蠅眼睛的形成及發(fā)育過(guò)程中一些必不可少的重要基因。
據(jù)美國(guó)“霍華德-休斯醫(yī)學(xué)研究所網(wǎng)站”日前報(bào)道，該研究所的烏特帕-班尼杰和他在美國(guó)加利福尼亞大學(xué)執(zhí)教的一個(gè)特殊的生物學(xué)習(xí)班的138名學(xué)生共同撰寫了這份研究報(bào)告。該報(bào)告向人們提供了對(duì)普通果蠅(黑腹果蠅Drosophila melanogaster)眼睛發(fā)育至關(guān)重要的第一個(gè)基因組范圍評(píng)估。
在有絲分裂重組中利用翻轉(zhuǎn)酶是一種標(biāo)準(zhǔn)化技術(shù)，常常被果蠅遺傳學(xué)家用來(lái)研究突變對(duì)果蠅產(chǎn)生的影響。班尼杰和他學(xué)生的真正成就是利用這種辦法在果蠅眼睛中制造出了同型結(jié)合突變(homozygous mutation)，并創(chuàng)建了一個(gè)描述突變顯型和表達(dá)的數(shù)據(jù)庫(kù)。其他研究人員也可以利用這些研究資料確定這些基因在其他組織中的功能。
Banerjee and his students identified 501 essential genes responsible for processes such as repair, cell death, and cell replication in the fruit fly's developing eye.
They report the results of their research and the impact of their research-based learning project in the February 2005 issue of PLoS (Public Library of Science) Biology.
It won't be easy to find a paper with 138 undergraduate authors, said Banerjee, one of 20 HHMI professors who received $1 million grants in 2002 to improve undergraduate biology education. In fact, this could easily be the first paper ever published with that many undergraduate authors that has serious science in it.
［簡(jiǎn)譯］美國(guó)霍華德-休斯醫(yī)學(xué)研究所的一名教授和他的138名學(xué)生日前發(fā)表了一份研究報(bào)告。這份報(bào)告首次確定了在果蠅眼睛的形成及發(fā)育過(guò)程中一些必不可少的重要基因。
據(jù)美國(guó)“霍華德-休斯醫(yī)學(xué)研究所網(wǎng)站”日前報(bào)道，該研究所的烏特帕-班尼杰和他在美國(guó)加利福尼亞大學(xué)執(zhí)教的一個(gè)特殊的生物學(xué)習(xí)班的138名學(xué)生共同撰寫了這份研究報(bào)告。該報(bào)告向人們提供了對(duì)普通果蠅(黑腹果蠅Drosophila melanogaster)眼睛發(fā)育至關(guān)重要的第一個(gè)基因組范圍評(píng)估。
在有絲分裂重組中利用翻轉(zhuǎn)酶是一種標(biāo)準(zhǔn)化技術(shù)，常常被果蠅遺傳學(xué)家用來(lái)研究突變對(duì)果蠅產(chǎn)生的影響。班尼杰和他學(xué)生的真正成就是利用這種辦法在果蠅眼睛中制造出了同型結(jié)合突變(homozygous mutation)，并創(chuàng)建了一個(gè)描述突變顯型和表達(dá)的數(shù)據(jù)庫(kù)。其他研究人員也可以利用這些研究資料確定這些基因在其他組織中的功能。