Once—daily pill could simplify HIV treatment
Myers Squibb and Gilead Sciences have combined many H.I.V.drugs into a single pill Sometimes the best medicine is more than one kind of medicine.Malaria,tuberculosis and H.I.V./AIDS,2 for example,are all treated with (1)of drugs.But that can mean a lot of pills to take.It would be____(2)if drug companies combined all the medicines into a single pill,taken just once a day.
Now,two companies say they have done that for people just____(3)treatment for H.I.V.,the virus that canses AIDS.The companies are Bristol-Myers Squibb and Gilead Sciences.They haye____(4)a single pill that combines three drugs currently 0/1the market.3 Bristol—Myers Squibb sells one of them____(5)the name of Sustiva.4 Gilead combined the____(6),Emtfiva and Viread,into a single.pill in two thousand four.
Combining drugs involves more than____(7)issues.It also involves issues of competition____(8)the drugs are made by different companies.The new once—daily pill is the result of____(9)is escribed as the first joint venture agreement of its kind in the treatment of H.I.V.
In January the New England Journal of Medicine5 published a study of the new pill.Researchers compared its____(10)to6 that of the widely use(combination of Sustiva and ombivir.Combivir____(11)two drugs,AZT7 and 3TC.8 The researchers say that after one year of treatment,the new pill suppressed H.I.V.1evels in more patients and with____(12)side effects.9 Gilead paid for the study.Professor Joel Gallant at the Johns Hopkins School of
Medicine in Baltimore,Maryland,led the research.He is a paid adviser to Gilead and Bristol—Meyers Squibb as well as the maker of Combivir,GlaxoSmithKline.加入收藏
Glaxo Smith Kline reacted____(13)the findings by saying thai:a single study.is of limited value.It says the effectiveness of Combivir has been shown in each of more than fifty studies.
The price of the new once—daily pill has not been announced.But Gilead and Bristol—Myers Squibb say they will provide it at reduced cost to developing countries.They plan in the next few months to ask the United States Food and Drug Administrationlo to—(14)the new pill.
There are limits to who could take it because of the different drugs it contains.For example,____(15)women are told not to take Sustiva because of the risk of bish disorders.11Experts say more than forty million people around the world are living with H.I.V.
詞匯:
malaria n.瘧疾tuberculosis n.結(jié)核(病) j(oint adj.聯(lián)合的,共同的 suppress
vt.抑制
pregnant aaj.妊娠的,有孕的
注釋:
1.HIV(human immunodeficieney virus):人免疫缺陷病毒
2.AIDS(acquired immunodeficiency syndrome):獲得性免疫缺陷綜合征,艾滋病
3.(be/7 come)on the market:出售
4.Sustiva以及后面出現(xiàn)的Emtriva、Viread和Combivir都是治療艾滋病藥物的商品名.
5.New England Journal of Medicine:新莢格蘭醫(yī)藥雜志.New England是美國東北六州(Maine,Vermont,New Hampshire.Massachusetts,Rhode Island和Connecticut)的總稱.
6.英國英語中compare with是“與…相比較”的意思,compare to是“把…比作…”的意思,但在美國英語中compare t0也有compare with的意思,這里就是“把…與…相比較”的意思.
7.AZT(Azidothymidine):疊氨胸苷(能抑制引起艾滋病的人免疫缺陷病毒)
8.3TC:拉夫米定(一種胞嘧啶核苷衍生物,能抑制乙肝病毒和人免疫缺陷病毒的逆轉(zhuǎn)錄酶的活性,改善肝臟組織的病變)
9.side effect:副作用
10.United States Food and Drug Administration(FDA):美國食品與藥晶管理局
11.birth disorder:先天性疾病
練習(xí):
1.A.conservation
B.eooperation
C.combinations
D.considerations
2.A.simpler
B.more complex
C.more meaningless
D.more troublesome
3.A.starting
B.stopping
C.ending
D.discontinuing
4.A.a(chǎn)nalyzed
B.examined
C.expiored
D.devekped
5.A.before
B.a(chǎn)fter
C.under
D.a(chǎn)bove
6.A.one
B.ones
C.other
D.others
7.A.social
B.technical
C.personal
D.histmqcal
8.A.if
B.a(chǎn)s if
C.though
D.a(chǎn)s though
9.A.that
B.which
C.what
D.whatever
10.A.size
B.shape
C.a(chǎn)ppearance
D.effectiveness
11.A.excludes
B.contains
C.looks like
D.tastes of
12.A.few
B fewer
C.many
D.more
13.A.for
B.with
C.to
D.Into
14.A.prove
B.disprove
C.improve
D.a(chǎn)pprove
15.A.weak
B.strong
C.elder
D.pregnant
1.C.本段中多處提到新藥是由幾種藥合成在一起的,而原來則需要服用多種藥物,本空白處四個(gè)選項(xiàng)中只有C項(xiàng)“組合物,結(jié)合體”是恰當(dāng)?shù)倪x擇.
2.A.其實(shí),本篇文章的標(biāo)題就提示了本空白處正確選項(xiàng).
3.A.這兩家研制新藥的公司讓誰服用這些新藥呢?只有A項(xiàng)“開始治療”的人才有意義,其它三項(xiàng)均不再治療,那有什么用呢?而且副詞just(“即將就要”)也起著幫助選擇的作用.
4.D.這兩家公司將目前市售的三種藥物合成一片,這只能是“開發(fā),研發(fā)”(D項(xiàng)),絕不能是“分析”、“檢查”、“探查”.
5.C.這幾個(gè)介詞中,只有under可以與name組合成短語under the name of(“以…名,名為…”),其它選項(xiàng)在這里均不合適.
6.D.上面提到兩家公司已經(jīng)開發(fā)出將多種藥合成為單片的新藥,Myers公司已合成了一種,Gilead公司則于2004年將其它兩種Emtriva和Viread合成為單片,這里既然列出了這兩種藥的名稱,所以就必須用“0thers”.
7.B.合成藥物讓人們首先想到的自然是“技術(shù)”問題,但不僅僅是技術(shù)問題,所以下旬就提到競爭問題.
8.A.競爭問題只有當(dāng)不同藥廠制造同一類藥品時(shí)才會(huì)出現(xiàn),所以只有if才合適.
9.C.本句中,the result of后面應(yīng)該是一個(gè)賓語從句,空白處應(yīng)該是賓語從句的主語,首先我們可以排除 that和which,因?yàn)樗鼈兪怯脕磉B接定語從句的,其它兩個(gè),what=the thing(s)that,whatever=any thing that,兩相比較,應(yīng)該what恰當(dāng),因?yàn)檫@里指的是具體這一次,而不是泛指任何一次.
10.D.研究人員對不同藥物進(jìn)行對比,自然是對比它們的療效,其它三個(gè)選項(xiàng)的對比均毫無意義.
11.B.四個(gè)選項(xiàng)中只有A和B可以考慮,exclude是“除外,排除”,與contain(“包含,含有”)正相反,因此,即使是不知道AZT和3TC可以治療艾滋病的人也會(huì)選擇B項(xiàng),因?yàn)樽髡呓^不會(huì)在沒有說明AZT和3TC是什么樣的藥物的請況下就說不包含它們,如果這樣就會(huì)讓讀者摸不著頭腦.
12.B.既然這種新藥可以抑制更多病人的HIV水平,副作用自然應(yīng)該“更少”,這是使用新藥前后的對比,故必須用比較級(jí).
13.C.react to(“對…作出反應(yīng)”)是固定用法,其它選項(xiàng)均不對.
14.D.從本句字面上看,他們打算在幾個(gè)月內(nèi)要求FDA干什么事情呢?而且是與新藥有關(guān),而FDA又是審批藥品的機(jī)關(guān),自然是approve(“批準(zhǔn)”)了.
15.D.本句后面已經(jīng)提到,生育時(shí)可能有危險(xiǎn),那就只有孕婦(pregnant women)才有生育的問題了.
Myers Squibb and Gilead Sciences have combined many H.I.V.drugs into a single pill Sometimes the best medicine is more than one kind of medicine.Malaria,tuberculosis and H.I.V./AIDS,2 for example,are all treated with (1)of drugs.But that can mean a lot of pills to take.It would be____(2)if drug companies combined all the medicines into a single pill,taken just once a day.
Now,two companies say they have done that for people just____(3)treatment for H.I.V.,the virus that canses AIDS.The companies are Bristol-Myers Squibb and Gilead Sciences.They haye____(4)a single pill that combines three drugs currently 0/1the market.3 Bristol—Myers Squibb sells one of them____(5)the name of Sustiva.4 Gilead combined the____(6),Emtfiva and Viread,into a single.pill in two thousand four.
Combining drugs involves more than____(7)issues.It also involves issues of competition____(8)the drugs are made by different companies.The new once—daily pill is the result of____(9)is escribed as the first joint venture agreement of its kind in the treatment of H.I.V.
In January the New England Journal of Medicine5 published a study of the new pill.Researchers compared its____(10)to6 that of the widely use(combination of Sustiva and ombivir.Combivir____(11)two drugs,AZT7 and 3TC.8 The researchers say that after one year of treatment,the new pill suppressed H.I.V.1evels in more patients and with____(12)side effects.9 Gilead paid for the study.Professor Joel Gallant at the Johns Hopkins School of
Medicine in Baltimore,Maryland,led the research.He is a paid adviser to Gilead and Bristol—Meyers Squibb as well as the maker of Combivir,GlaxoSmithKline.加入收藏
Glaxo Smith Kline reacted____(13)the findings by saying thai:a single study.is of limited value.It says the effectiveness of Combivir has been shown in each of more than fifty studies.
The price of the new once—daily pill has not been announced.But Gilead and Bristol—Myers Squibb say they will provide it at reduced cost to developing countries.They plan in the next few months to ask the United States Food and Drug Administrationlo to—(14)the new pill.
There are limits to who could take it because of the different drugs it contains.For example,____(15)women are told not to take Sustiva because of the risk of bish disorders.11Experts say more than forty million people around the world are living with H.I.V.
詞匯:
malaria n.瘧疾tuberculosis n.結(jié)核(病) j(oint adj.聯(lián)合的,共同的 suppress
vt.抑制
pregnant aaj.妊娠的,有孕的
注釋:
1.HIV(human immunodeficieney virus):人免疫缺陷病毒
2.AIDS(acquired immunodeficiency syndrome):獲得性免疫缺陷綜合征,艾滋病
3.(be/7 come)on the market:出售
4.Sustiva以及后面出現(xiàn)的Emtriva、Viread和Combivir都是治療艾滋病藥物的商品名.
5.New England Journal of Medicine:新莢格蘭醫(yī)藥雜志.New England是美國東北六州(Maine,Vermont,New Hampshire.Massachusetts,Rhode Island和Connecticut)的總稱.
6.英國英語中compare with是“與…相比較”的意思,compare to是“把…比作…”的意思,但在美國英語中compare t0也有compare with的意思,這里就是“把…與…相比較”的意思.
7.AZT(Azidothymidine):疊氨胸苷(能抑制引起艾滋病的人免疫缺陷病毒)
8.3TC:拉夫米定(一種胞嘧啶核苷衍生物,能抑制乙肝病毒和人免疫缺陷病毒的逆轉(zhuǎn)錄酶的活性,改善肝臟組織的病變)
9.side effect:副作用
10.United States Food and Drug Administration(FDA):美國食品與藥晶管理局
11.birth disorder:先天性疾病
練習(xí):
1.A.conservation
B.eooperation
C.combinations
D.considerations
2.A.simpler
B.more complex
C.more meaningless
D.more troublesome
3.A.starting
B.stopping
C.ending
D.discontinuing
4.A.a(chǎn)nalyzed
B.examined
C.expiored
D.devekped
5.A.before
B.a(chǎn)fter
C.under
D.a(chǎn)bove
6.A.one
B.ones
C.other
D.others
7.A.social
B.technical
C.personal
D.histmqcal
8.A.if
B.a(chǎn)s if
C.though
D.a(chǎn)s though
9.A.that
B.which
C.what
D.whatever
10.A.size
B.shape
C.a(chǎn)ppearance
D.effectiveness
11.A.excludes
B.contains
C.looks like
D.tastes of
12.A.few
B fewer
C.many
D.more
13.A.for
B.with
C.to
D.Into
14.A.prove
B.disprove
C.improve
D.a(chǎn)pprove
15.A.weak
B.strong
C.elder
D.pregnant
1.C.本段中多處提到新藥是由幾種藥合成在一起的,而原來則需要服用多種藥物,本空白處四個(gè)選項(xiàng)中只有C項(xiàng)“組合物,結(jié)合體”是恰當(dāng)?shù)倪x擇.
2.A.其實(shí),本篇文章的標(biāo)題就提示了本空白處正確選項(xiàng).
3.A.這兩家研制新藥的公司讓誰服用這些新藥呢?只有A項(xiàng)“開始治療”的人才有意義,其它三項(xiàng)均不再治療,那有什么用呢?而且副詞just(“即將就要”)也起著幫助選擇的作用.
4.D.這兩家公司將目前市售的三種藥物合成一片,這只能是“開發(fā),研發(fā)”(D項(xiàng)),絕不能是“分析”、“檢查”、“探查”.
5.C.這幾個(gè)介詞中,只有under可以與name組合成短語under the name of(“以…名,名為…”),其它選項(xiàng)在這里均不合適.
6.D.上面提到兩家公司已經(jīng)開發(fā)出將多種藥合成為單片的新藥,Myers公司已合成了一種,Gilead公司則于2004年將其它兩種Emtriva和Viread合成為單片,這里既然列出了這兩種藥的名稱,所以就必須用“0thers”.
7.B.合成藥物讓人們首先想到的自然是“技術(shù)”問題,但不僅僅是技術(shù)問題,所以下旬就提到競爭問題.
8.A.競爭問題只有當(dāng)不同藥廠制造同一類藥品時(shí)才會(huì)出現(xiàn),所以只有if才合適.
9.C.本句中,the result of后面應(yīng)該是一個(gè)賓語從句,空白處應(yīng)該是賓語從句的主語,首先我們可以排除 that和which,因?yàn)樗鼈兪怯脕磉B接定語從句的,其它兩個(gè),what=the thing(s)that,whatever=any thing that,兩相比較,應(yīng)該what恰當(dāng),因?yàn)檫@里指的是具體這一次,而不是泛指任何一次.
10.D.研究人員對不同藥物進(jìn)行對比,自然是對比它們的療效,其它三個(gè)選項(xiàng)的對比均毫無意義.
11.B.四個(gè)選項(xiàng)中只有A和B可以考慮,exclude是“除外,排除”,與contain(“包含,含有”)正相反,因此,即使是不知道AZT和3TC可以治療艾滋病的人也會(huì)選擇B項(xiàng),因?yàn)樽髡呓^不會(huì)在沒有說明AZT和3TC是什么樣的藥物的請況下就說不包含它們,如果這樣就會(huì)讓讀者摸不著頭腦.
12.B.既然這種新藥可以抑制更多病人的HIV水平,副作用自然應(yīng)該“更少”,這是使用新藥前后的對比,故必須用比較級(jí).
13.C.react to(“對…作出反應(yīng)”)是固定用法,其它選項(xiàng)均不對.
14.D.從本句字面上看,他們打算在幾個(gè)月內(nèi)要求FDA干什么事情呢?而且是與新藥有關(guān),而FDA又是審批藥品的機(jī)關(guān),自然是approve(“批準(zhǔn)”)了.
15.D.本句后面已經(jīng)提到,生育時(shí)可能有危險(xiǎn),那就只有孕婦(pregnant women)才有生育的問題了.