正交法探討?yīng)毣罴纳诜禾崛」に?/h1>

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摘要:采用正交試驗(yàn)方法,對獨(dú)活寄生口服液提取工藝 條件進(jìn)行優(yōu)選。試驗(yàn)結(jié)果表明,對含揮發(fā)性成分的藥材加8倍水,浸泡0.5 h,水蒸氣蒸餾; 母液及殘?jiān)c處方中其它藥材合并加8倍水,浸泡0.5 h,水提取兩次,1 h/次,醇沉濃度為 70%。
    關(guān)鍵詞:獨(dú)活寄生口服液; 正交法; 提取工藝
    中圖分類號:R284.2  文獻(xiàn)標(biāo)識碼:A   文章編號:1008-0805(2000)07-0594-02
    Studies on the Abstraction Technology of Duhuo Jisheng Oral Liquid by Orthogonal Design
    GAO Yue-lai, SHEN Lie-hang
    (Shandong Provincial Hospital, Jinan 250021, China)
    Abstract:Select the best abstraction method for Duhuo Jishe ng Oral Liquid by orthogonal design. Result:soaking oil herbs for 0.5 h in 8 tim es of water, then distil by steam; the mother liquid and residue combine with ot her herbs in 8 times of water, soaking for 0.5 h, and then abstract two times by water for one hour each time. The concentration of the alcohol for precipitate is 70 percent.
    Key words:Duhuo Jisheng oral liquid; Orthogonal d esign; Abstraction technology
    獨(dú)活寄生口服液是在獨(dú)活寄生湯(《千金要方》方)基礎(chǔ)上研制成的新制劑,由獨(dú)活、寄生、 當(dāng)歸、黨參、防風(fēng)、白芍、甘草等中藥組成,具有祛風(fēng)濕、止痹痛、益肝腎、補(bǔ)氣血等功能 。在工藝研究時(shí),我們采用L9(34)正交表進(jìn)行試驗(yàn),探討提取工藝條件。
    1 試驗(yàn)方法
    1.1 正交試驗(yàn)設(shè)計(jì)
    根據(jù)傳統(tǒng)湯劑的提取方法和藥材所含有效成分的性質(zhì),我們采用蒸餾法與水提醇沉法相結(jié)合 的提取工藝,選用加水量、浸泡時(shí)間、提取時(shí)間、醇沉濃度作為考察因素,以測定相對密度 、揮發(fā)油的含量和觀察澄明度為考察指標(biāo),選用L 9(34)正交法進(jìn)行試驗(yàn)。